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hyperprolactinemia

Hyperprolactinemia is the over production of the prolactin hormone (the milk-producing hormone) by the pituitary gland. Hyperprolactinemia interferes with the normal functioning of the hypothalamus and, as a result, prevents ovulation (egg release).
  • symptoms
  • cause
  • treatment

symptoms

In women, the symptoms of this disorder include galactorrhoea (the production of milk by women who are not breast-feeding) and anovulation. Heightened prolactin levels can be identified through a blood test.

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cause

Hyperprolactinemia can be caused by a variety of factors such as:

  • Benign swellings (tumours) of the pituitary (called prolactinoma).
  • Thyroid gland disorders.
  • Some medications, such as antihypertensive (high blood-pressure) therapies and nausea medication.
  • Oral contraceptives and illegal drugs (such as marijuana).

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treatment

Treatment will depend on the underlying cause. A closer examination of the head (MRI scan) may be necessary in order to exclude the possibility of a prolactinoma or a thyroid gland tumour, especially if in the presence of other symptoms such as hazy eyesight.

A variety of medication and surgical methods can be used to treat hyperprolactinemia:

  1. Bromocriptine is used to reduce excessive prolactin levels.
  2. Clomiphene is sometimes used to stimulate ovulation.
  3. Surgery is only employed to remove potential tumours (a more risky procedure).

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